I have replaced my multiple monitor configuration on my PC, it was 1*27 inch and 1*32 inch monitors, by a single 42 inch 4k monitor from LG. To be precise a LG 43UD79-B 108.98 cm (42.51 inch).
Like a dog with two tails, I do not know which one to wag first.
The only change I needed to do was to get a deeper desk so that I can set the screen about 15 cms further away.